
AGENDA
THURSDAY, March 20, 2025
7:00 AM–4:30 PM
Registration
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7:15–8:00 AM
Breakfast
Pediatric Connect I Breakout Session
Co-chairs/moderators: Carina Kugelmas, MD and Miriam Vos, MD, MSPH
8:00–8:10 AM
Welcome
Miriam Vos, MD, MSPH
Part I: Hepatology Potpourri
Moderators: Miriam Vos, MD, MSPH and Rohit Kohli, MBBS, MS
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8:10–8:30 AM
Lipodystrophy: Finding the Needle in the Haystack
Rebecca Brown, MD, MHSc
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8:30–8:45 AM
Modern Approaches in Mitochondrial Liver Disease
Ronald Sokol, MD
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8:45–9:15 AM
Cases for Contemplation: Panel Discussion – Case-Based
Rebecca Brown, MD, MHSc; Ryan Fischer, MD; Samar Ibrahim, MB, ChB; Ronald Sokol, MD; and Jeffrey Teckman, MD
Part II: Hepatology Potpourri
Moderators: Rima Fawaz, MD and Ronald Sokol, MD
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9:15–9:40 AM
Keynote: Wilson Disease Emerging Challenges
Michael Schilsky, MD
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9:40–10:00 AM
Cases for Contemplation: Panel Discussion – Case-Based
Regino Gonzalez-Peralta, MD; Alyssa A. Kriegermeier, MD; Anna Peters, MD, PhD; and Michael Schilsky, MD
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10:00–10:15 AM
Break
Part III: Pediatric Cholestatic Disease
Moderators: Regino Gonzalez-Peralta, MD and Nitika Gupta, MD
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10:15–10:30 AM
Nutritional Management: New Guidelines on Managing Fat-Soluble Vitamin Deficiency
Amal Aqul, MD
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10:30–10:45 AM
VOUS or Not? Clinical use of Genetic Panels for Cholestatic Disease
Kathleen Loomes, MD
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10:45–11:00 AM
Making the Case for Pruritus Treatment: Case-Based Examples of Therapeutic Decision-Making
Mercedes Martinez, MD
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11:00–11:30 AM
Cases for Contemplation: Panel Discussion – Case-Based
Amal Aqul, MD; Jaime Chu, MD; Karan Emerick, MD; Kathleen Loomes, MD; and Mercedes Martinez, MD
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11:30–11:45 AM
Pediatric Connect Closing
Carina Kugelmas, MD
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11:45 AM–12:15 PM
Lunch​
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12:15–1:00 PM
Industry-Sponsored Event
Iqirvo & Bylvay: Discover Treatment Options for Your Patients
Naim Alkhouri, MD
Sponsored by: Ipsen Biopharmaceuticals
La Cantera Ballroom
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1:00–1:15 PM
Break/Visit Exhibits
1:15–1:30 PM
Welcome and Introductions
Zobair Younossi, MD, MPH
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1:30–2:00 PM
Keynote: Finding Happiness in Your Career
Patrick Kamath, MD
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Session I: Autoimmune Cholestatic Liver Disease
Advances in PBC, PSC, and Autoimmune Hepatitis
Co-chairs: Kris Kowdley, MD and Raj Vuppalanchi, MD
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2:00–2:20 PM
Current Landscape in PBC Diagnosis and Treatment
Kris Kowdley, MD
2:20–2:35 PM
Debate: Second-Line Therapy Options in PBC
Moderator: John Vierling, MD
Aparna Goel, MD and Craig Lammert, MD
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2:35–2:55 PM
Assessment and Therapy of Symptoms in PBC
Mark Swain, MD, MSc
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2:55–3:15 PM
Q&A / Panel Discussion
3:15–3:30 PM
Break / Visit Exhibits
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3:30–3:45 PM
Spotlight on Drug-Induced Autoimmune Hepatitis and Immune-Mediated Liver Injury from Checkpoint Inhibitors
Lily Dara, MD
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3:45–4:00 PM
Overview of PSC: Mechanisms and Emerging Therapies
​Christopher Bowlus, MD
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4:00–4:15 PM
Updates in Autoimmune Hepatitis
Craig Lammert, MD
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4:15–4:30 PM
Q&A / Panel Discussion
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4:30–4:45 PM
Break / Visit Exhibits
Session II: Alcohol-Associated Liver Disease
New Horizons in Treating Alcohol-Associated Hepatitis: Therapies, Strategies, and Debates
Co-chairs: Steven Flamm, MD; Mack Mitchell, MD; and Ashwani Singal, MD, MS
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4:45–5:05 PM
Recognition and Treatment of Compensated ALD/MetALD
Ashwani Singal, MD, MS
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5:05–5:25 PM
Treatment of AUD in Patients with ALD
Mack Mitchell, MD
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5:25–5:45 PM
Early Liver Transplant for ALD: What Defines Success After Transplant?
Sarah Lieber, MD, MSCR
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5:45–6:00 PM
Q&A / Panel Discussion
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6:00–7:00 PM
Satellite Symposium (Non-Accredited)
Expert Perspectives on the Unmet Needs in Patients With Wilson Disease
Sammy Saab, MD, MPH and Regino Gonzalez-Peralta, MD
Supported by an educational grant from Orphalan.
FRIDAY, March 21, 2025
7:00 AM–4:45 PM
Registration
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7:15–7:45 AM
Breakfast
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7:45–8:30 AM
Industry-Sponsored Event
A Deep Dive into MASH: Exploring the Role of Metabolic Dysfunction in Disease Pathophysiology
Steven Flamm, MD
Sponsored by: Novo Nordisk
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8:30–9:00 AM
Break / Visit Exhibits
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Session III: MASLD/MASH
Innovations in MASLD Management: From NITs to Multidisciplinary Approaches and Extrahepatic Comorbidities
Co-chairs: Alina Allen, MD and Zobair Younossi, MD, MPH
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9:00–9:05 AM
Welcome Back
Zobair Younossi, MD, MPH
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9:05 AM–9:35 AM
Keynote: The Evolution of MASH and Fibrosis Over Decades
Scott Friedman, MD
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9:35 AM–9:50 AM
Practical Use of NITs
Alina Allen, MD
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9:50–10:15 AM
Expert Panel Discussion: The Role of NITs
Moderator: Naim Alkhouri, MD
Panelists: Alina Allen, MD; Mandeep Bajaj, MD; and Scott Friedman, MD
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10:15–10:30 AM
Break / Visit Exhibits
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10:30–10:45 AM
Current Management: Obesity and Type-2 Diabetes in MASLD
Christos Mantzoros, MD
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10:45–11:00 AM
MASH Targeted Therapy-Current and Future
Manal Abdelmalek, MD, MPH
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11:00–11:25 AM
Expert Panel Discussion: Management of MASLD
Moderator: Zobair Younossi, MD, MPH
Panelists: Manal Abdelmalek, MD, MPH; Mandeep Bajaj, MD; Scott Isaacs, MD; and Christos Mantzoros, MD, DSc, PhD
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11:25–11:40 AM
Extrahepatic Diseases Associated with MASLD (CVD, CKD, Cancer, and Sarcopenia)
Naim Alkhouri, MD
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11:40–11:55 AM
Role of Multi-Disciplinary Team in MASLD Management
Mazen Noureddin, MD, MHSc
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11:55 AM–12:20 PM
Expert Panel Discussion: Models of Care
Moderator: Sonal Kumar, MD MPH
Panelists: Michael Betel, MS, MSc; Scott Isaacs, MD; Christos Mantzoros, MD, DSc, PhD; and Mazen Noureddin, MD, MHSc
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12:20–12:30 PM
Session Wrap-up
Zobair Younossi, MD, MPH
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12:30–1:00 PM
Lunch
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1:00–1:45 PM
Industry-Sponsored Event
Clinical Deep Dive: Unlocking the Treatment Potential of Rezdiffra
Sujit Janardhan, MD and Carmen Landaverde, MD
Sponsored by: Madrigal Pharmaceuticals
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1:45–2:00 PM
Break / Visit Exhibits
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Session IV: Cirrhosis
Advancing Care in Cirrhosis: A Case-Based Approach to Alpha-1 Antitrypsin Deficiency, Portal Hypertension, and Acute-on-Chronic Liver Failure
Co-chairs: Marcelo Kugelmas, MD and Sammy Saab, MD, MPH
2:00–2:10 PM
Session Introduction
Marcelo Kugelmas, MD
2:10–2:40 PM
Part I: Alpha-1 Antitrypsin Deficiency and Cirrhosis
Ranjeeta Bahirwani, MD; Arun Jesudian, MD; Paul Kwo, MD; Mina Rakoski, MD; and Sammy Saab, MD, MPH
2:40–3:10 PM
Part II: Cirrhosis and Portal Hypertension
Marcelo Kugelmas, MD; Carmen Landaverde, MD; Akshay Shetty, MD; and Robert Wong, MD, MS
3:10–3:40 PM
Part III: Acute-on-Chronic Liver Failure
David S. Goldberg, MD, MSCE; Sammy Saab, MD, MPH; Monica Tincopa, MD, MS; Hirsh D. Trivedi, MD, MS; and Kali Zhou, MD
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3:40–3:45 PM
Case Wrap-up
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3:45–4:00 PM
Break / Visit Exhibits
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4:00–4:05 PM
Keynote Introduction
Marcelo Kugelmas, MD
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4:05–4:35 PM
Keynote: Management of Portal Vein Thrombosis
Steven Flamm, MD
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4:35–4:50 PM
Q&A / Panel Discussion
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4:50–5:00 PM
Wrap-up
Marcelo Kugelmas, MD
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5:00–6:00 PM
Accredited Symposium
Bridging the Gap: Strategies to Advance Equity in Liver Disease Care
Kimberly Brown, MD, Lily Dara, MD, Nadege Gunn, MD, CPI, Tatyana Kushner, MD, MSCE, and Nancy Reau, MD
Supported by an educational grant from Gilead Sciences, Inc.
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6:00–7:00 PM I Breakout Session
Pediatric MASLD Roundtable Discussion
Co-chairs: Carina Kugelmas, MD and Miriam Vos, MD, MSPH
Rohit Kohli, MBBS, MS; Marialena Mouzaki, MD, MSc; Jennifer Panganiban, MD;
Jeffrey Schwimmer, MD; and Stavra Xanthakos, MD, MS
7:00–8:30 PM
Conference Reception & Poster Display
SATURDAY, March 22, 2025
7:15–7:45 AM
Breakfast
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7:45–8:30 AM
Industry-Sponsored Event
Clinical Insights Into a First-in-Class Treatment for Primary Biliary Cholangitis (PBC)
Kimberly Brown, MD
Sponsored by: Gilead Sciences
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8:30–9:00 AM
Break / Visit Exhibits
9:00–9:05 AM
Welcome Back
Ira Jacobson, MD
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Session V: Viral Hepatitis
Co-chairs: Ira Jacobson, MD and Paul Martin, MD
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9:00–9:20 AM
Exploring the Nuances of Hepatitis Vaccination: Are We Doing Enough?
Paul Kwo, MD ​
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9:20–9:40 AM
Navigating Expanding Guidelines for Hepatitis B: Which Are Right for Your Patients?
Douglas Dieterich, MD
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9:40–10:00 AM
Emerging Treatments for Hepatitis B on the Horizon
Ira Jacobson, MD
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10:00–10:20 AM
Hepatitis D: Strategies for Treatment and Management
Tatyana Kushner, MD, MSCE
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10:20–10:40 AM
HBV Case Discussion
Moderated by Paul Martin, MD
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10:40–11:00 AM
Q&A / Panel Discussion
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11:00–11:15 AM
Break / Visit Exhibits
Session VI: HCC
Advances in Liver Cancer Therapy: IR, Systemic Treatments, and Neoadjuvant Approaches
Co-chairs: Aijaz Ahmed, MD; Laura Kulik, MD; and Robert Wong, MD, MS
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11:15–11:30 AM
Locoregional Therapy for Locally Advanced HCC
Siddharth Padia, MD
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11:30–11:40 AM
How Do Systemic Therapies and LRT Fit into the Treatment of Unresectable HCC?
Laura Kulik, MD
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11:40–11:55 AM
Evolving Role of Neoadjuvant Systemic Therapy for Transplant
Parissa Tabrizian, MD
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11:55 AM–12:15 PM
Q&A / Panel Discussion
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12:15–12:30 PM
Closing Remarks
Marcelo Kugelmas, MD
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1:30–3:00 PM I Breakout Session
APP Session
Aijaz Ahmed, MD, Christina Hanson, FNP and Marcelo Kugelmas, MD
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1:30–3:30 PM I Breakout Session
Fellows Summit
Kimberly Brown, MD, Steven Flamm, MD and Robert Wong, MD